JLABS/Children's National

Johnson & Johnson Innovation, Children's National Health System collaborate

BARDA will collaborate with JLABS to develop, maintain a specialized innovation zone; QuickFire Challenge looks to accelerate pediatric-centered innovation.

April 17, 2019

Posted by Elizabeth Engler Modic

Design Devices/Implants

Officials from Johnson & Johnson Innovation LLC and Children's National Health System (Children's National) announce a collaboration to launch JLABS @ Washington, DC, a 32,000ft² facility to be located at the new Children's National Research and Innovation Campus in Washington, DC. This Children's National expansion is set on a nearly 12-acre portion of the former Walter Reed Army Medical Center campus in the nation's capital. The co-location of the Research and Innovation Campus with key partners in the areas of public health research, innovation, and incubator space is critical to accelerating the translation of potential breakthrough discoveries into new treatments and technologies. The JLABS @ Washington, DC site will be open to pharmaceutical, medical device, consumer and health technology companies that are aiming to advance the development of new drugs, medical devices, precision diagnostics and health technologies, including applications in pediatrics.

This collaboration marks the second time Johnson & Johnson and Children's National have teamed up to emphasize the importance of investing in the health and well-being of babies and children around the world. Through either sponsorship or membership, both entities founded Safe Kids Worldwide, a nonprofit organization aiming to help families and communities keep kids safe from injuries.

Children's National leads the FDA-funded National Capital Consortium for Pediatric Device Innovation in collaboration with the University of Maryland, College Park. The consortium has provided mentorship support to more than 60 medical device startups to help advance their pediatric innovations. Five of the devices assisted by this program have received either CE Mark approval or FDA market clearance. Children's National has also spun out more than 20 start-up companies from its own intellectual property.

Children's National is currently ranked 7th in National Institutes of Health (NIH) research funding among pediatric hospitals. The new campus will allow Children's National to expand its research programs. A key area of expansion when the campus opens will be high-impact opportunities in pediatric genomic and precision medicine, anchored by the organization's Center for Genetic Medicine Research and Rare Disease Institute. Its proximity to federal research institutions and agencies, universities, and academic research centers enables the new Children's National campus to leverage the rich ecosystem of the public and private sectors to help bolster innovation.

Johnson & Johnson Innovation seeks to find the best science and technology, no matter where it is located, aiming to solve the greatest unmet medical and healthcare needs of our time. JLABS, in addition to offering emerging life science companies modular lab units, office space, shared core laboratory equipment and business facilities, will link the entrepreneurs within the District and across the greater Virginia and Maryland regions with the full breadth of the Johnson & Johnson Innovation model, including opportunities for funding, third-party services, educational events and R&D experts from medical technology, consumer healthcare product and Janssen pharmaceutical teams. In addition to providing access to scientific, industry and capital funding experts from across the industry, JLABS @ Washington, DC will also follow the same no-strings attached approach currently in operation in San Diego; San Francisco; South San Francisco; Boston; Lowell, MA; Houston; Toronto; New York City; Beerse, Belgium; and Shanghai, China (opening June 2019).

JLABS @ Washington, DC to provide residency for emerging companies dedicated to improving the speed and effectiveness of a medical countermeasure response to emerging pathogens and health security threats the nation faces
As part of the JLABS @ Washington, DC launch, the Biomedical Advanced Research and Development Authority (BARDA), a component of the Office of the Assistant Secretary for Preparedness and Response in the U.S. Department of Health and Human Services, will collaborate with Johnson & Johnson Innovation – JLABS to develop and maintain a specialized innovation zone that will be dedicated to the advancement of medical countermeasures aimed at securing our nation from chemical, biological, radiological, and nuclear (CBRN) threats, as well as from pandemic influenza and emerging infectious diseases. The innovation zone will provide residency for eligible companies and entrepreneurs focused on solutions with the potential to improve our nation's response capacity and capabilities to address 21st century health security threats.

This agreement further builds on established collaborations between Janssen Research & Development LLC (Janssen) and BARDA to accelerate new therapies and vaccines to protect communities against these threats and seeks to leverage JLABS' experience catalyzing communities of entrepreneurs, investors and thought leaders to further promote and support the development of related treatments and prevention solutions.

QuickFire Challenge to accelerate pediatric-centered innovation
Johnson & Johnson Innovation is proud to be among those answering the call to prioritize pediatric care, a message widely celebrated at the 2018 State of the Union address alongside the promise of an additional $500 million in government funding for pediatric oncology research over the next 10 years.

To mark the launch of the new JLABS on the Children's National campus and the collaboration with BARDA, JLABS announced the JLABS @ Washington, DC Children's QuickFire Challenge aiming to accelerate the development and commercialization of pediatric-centered healthcare innovation. Innovators with the best ideas, technologies, or solutions that impact pediatric oncology, pediatric surgical care, and influenza will receive up to $150,000 in grant funding, residency at JLABS @ Washington, DC with the use of a bench, workstation and access to the JLABS @ Washington, DC community for one year, and mentoring from across the Johnson & Johnson Family of Companies.

The JLABS @ Washington, DC Children's QuickFire Challenge encourages innovators to submit their ideas starting today, April 9, 2019 through February 7, 2020. The awardee(s) will be announced in 2020. For more information about the application process, please visit https://jlabs.tv/DC.

JLABS facilities have incubated more than 500 companies to date and are currently home to over 330 companies advancing pharmaceutical, medical device, consumer, and health technology programs. More than 120 collaborations have been formed between companies working with JLABS and the Johnson & Johnson Family of Companies.

Applications to join JLABS @ Washington, DC and other JLABS sites are currently being accepted from biotech, pharmaceutical, medical device, consumer health, and health technology companies.

The graph includes the 12-month moving average for the durable goods shipments and cutting tool orders. These values are calculated by taking the average of the most recent 12 months and plotting them over time.

USCTI/AMT

US cutting tool consumption up 8% in February

With a year-to-date total of $420.7 million, 2019 is up 13% when compared with 2018.

April 16, 2019

Posted by Elizabeth Engler Modic

Economy/M&A Tooling/Workholding

Cleveland, Ohio – February 2019 U.S. cutting tool consumption totaled $205.6 million according to the U.S. Cutting Tool Institute (USCTI) and AMT – The Association For Manufacturing Technology. This total, as reported by companies participating in the Cutting Tool Market Report collaboration, was down 4.4% from January’s $215.1 million and up 8% when compared with the $190.3 million reported for February 2018. With a year-to-date total of $420.7 million, 2019 is up 13% when compared with 2018.

These numbers and all data in this report are based on the totals reported by the companies participating in the CTMR program. The totals here represent a significant market share of the U.S. market for cutting tools.

“The 8% year over year increase posted in February reflects the continuing strength in the U.S. manufacturing base. We are hearing of signs that the market’s growth rate may slow later this year but February’s results are getting the year off to a good start,” says Phil Kurtz, president of USCTI.

According to Greg Daco, Chief US Economist at Oxford Economics, “Cutting tool shipments are off to a solid start in 2019, bucking the trend of cooler momentum in the broader durable goods category. A very solid 13% gain in year-to-date cutting tool shipments through February puts the category well ahead of the healthy 6% year-to-date rise in overall durable goods shipments. Leading manufacturing activity indicators point to healthy, but gradually cooling momentum in 2019. Slower global growth, lingering trade tensions, and reduced fiscal stimulus will weigh on growth while elevated private sector confidence, a solid labor market and a more dovish Fed support activity.”

February 2019 U.S. Manufacturing Technology Orders

AMT/USMTO

February 2019 manufacturing technology orders slow

While orders declined, levels remain good; March Manufacturing ISM Report On Business registered a PMI of 55.3%, an expansion of 1.1 percentage points.

April 15, 2019

Posted by Elizabeth Engler Modic

Manufacturing

McLean, Va. (April 8, 2019) – Manufacturing technology orders totaled $337.2 million in February 2019, a 15% decline from January and a 7% decline from the previous February, according to the latest USMTO report from AMT. The year-to-date total was $735.2 million, less than 1% off the year-to-date total at this point last year.

“It’s important to look at the February numbers in context. It’s true that order levels declined, but from the second strongest January in the history of the USMTO program. They’re still at good levels compared to this time a year ago,” said Douglas K. Woods, President, AMT. “Other indicators signal continued manufacturing strength. AMT members are generally positive heading into the second quarter; the U.S.-China tariff negotiations look to be moving toward a successful conclusion; and the March ISM Manufacturing PMI showed expansion which beat analysts’ expectations and rallied the stock market. However, uncertainty lingers on issues such as tax, trade, and the budget, and continued inaction in Washington could stall already sluggish growth.”

While companies in many industries reduced their orders in February, the nearly 50% decline in orders placed by aerospace as well as engine and turbine industries led the downturn between January and February. The automotive sector recorded a modest double-digit uptick. Bucking the general trend, February 2019 had a notable expansion in orders from commercial and service industry machinery manufacturing such as water treatment and commercial cleaning equipment. The big gain was the result of large orders in the Great Lakes area and the West.

Four of the six USMTO regions had fewer orders in February than January, with the largest decline coming from the Southeast. In the West, metal cutting orders rose slightly. However, declines in forming and fabricating lead to roughly stagnant orders compared to the previous month. The South-Central region outperformed all other regions, with orders expanding by over a third from January 2019 led by growth in oil & gas, contract machining, and food processing equipment sectors.

Capacity utilization had a second month of declines in February, settling at 77%, off the post-recession high of 77.8% in December 2018. Despite an increase in orders from the automotive sector, light vehicle sales rebounded to 17.477 million annualized units in March. March Manufacturing ISM Report On Business registered a Purchasing Manager’s Index of 55.3%, an expansion of 1.1 percentage points over February, signaling underlying strength in the manufacturing sector.

Medical design, manufacturing, advancements

The week gets busy so in case you missed these top medical stories, below is a recap.

April 13, 2019

Posted by Elizabeth Engler Modic

Blog

3D printed tissues may keep athletes in action

Bioscientists are moving closer to 3D-printed artificial tissues to help heal bone and cartilage typically damaged in sports-related injuries to knees, ankles, and elbows.

Scientists at Rice University and the University of Maryland reported their first success at engineering scaffolds that replicate the physical characteristics of osteochondral tissue – basically, hard bone beneath a compressible layer of cartilage that appears as the smooth surface on the ends of long bones.

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Black bear takes a plant tour at Denso

A bear barged into Denso’s Maryville, Tennessee facility earlier this week.

DENSO Manufacturing employees were warned about a bear roaming around the facility Tuesday. By Wednesday the black bear was seen on video footage taking a tour of the manufacturing facility.

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Sandvik creates smash-proof, 3D printed guitar

Rock stars have been smashing guitars for decades, few with more enthusiasm than Swedish-born guitar virtuoso Yngwie Malmsteen. Global engineering company Sandvik decided to test its cutting-edge techniques by building the world’s first all-metal, unbreakable guitar and letting Malmsteen unleash his smashing skills.

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Beaumont Machine relocates, starts a new chapter

As company president Ed Beaumont explains, “We needed a fresh start and we were committed to making it happen, on every level, from our physical location to the machine offerings to the markets served and more.”

And Beaumont Machine has done exactly that with the opening of its new manufacturing facility in the Cincinnati area – 4001 Borman Dr., Batavia, Ohio 45103; 513.701.0421; www.beaumontmachine.com.

Johnson & Johnson Innovation, Children's National Health System collaborate

US cutting tool consumption up 8% in February

February 2019 manufacturing technology orders slow

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Medical design, manufacturing, advancements

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