Zavation unveils advanced multimaterial cervical interbody implant

Zavation Medical Products, LLC announces the release of its most advanced cervical interbody implant to date – the integration of NanoPrime Titanium Ion Bond Technology with the company's proprietary Labyrinth porous PEEK architecture. This combination is engineered to elevate the mechanical advantages of PEEK with the biological benefits of titanium.         

NanoPrime utilizes a cutting-edge nano-engineering process involving evaporation and ion beam bombardment in a high vacuum environment. This technique allows intermixing of coating and substrate atoms, improving adhesion and minimizing risk of delamination, unlike conventional coatings.

Rather than relying on a single material's strengths, Zavation's NanoPrime Labyrinth Cervical Interbody leverages the complementary benefits of two proven technologies:

NanoPrime, a nano-textured titanium ion bond surface, creates a high-adhesion, nano-textured surface shown to support cellular activity associated with bone formation

Labyrinth, Zavation's patented porous PEEK structure, designed to mimic cancellous bone architecture and improve the biological response compared to smooth PEEK or traditional solid structures.

Combined, these technologies deliver an implant platform that maintains the imaging clarity and elastic modulus of PEEK while introducing an osteoconductive nano-surface intended to promote early cell attachment, induce hydrophilic wicking, and reduce stress shielding.

“The NanoPrime Labyrinth Cervical Interbody reflects the kind of design philosophy I look for in an implant – thoughtful engineering that supports early bone integration and long-term stability,” says Dr. Freeland Ackley, a fellowship-trained spine surgeon specializing in degenerative, revision, and minimally invasive spine procedures for the comprehensive treatment of cervical, thoracic, and lumbar conditions. “The combination of porous architecture with a nano-textured titanium interface gives me confidence in the construct I'm using in my practice.”

A cohesive biological environment – inside and out

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By applying NanoPrime to the porous Labyrinth structure, Zavation has created a fully integrated surface environment – from the macro-porous architecture to the nano-textured titanium interface. This synergy is engineered to:

• Encourage bony integration throughout the porous network
• Promote osteogenic cellular behavior associated with accelerated fusion
• Maintain mechanical properties and visualization advantages valued by surgeons
• Provide a predictable, uniform surface across the entire implant geometry

“The NanoPrime Labyrinth Cervical interbody represents the next step in strengthening our platform of interbody materials and structures, giving distributors and surgeons greater design and stiffness modalities,” says Derek Kuyper, chief executive officer of Zavation. “By integrating NanoPrime and Labyrinth technologies into our cervical line, we're offering a world first interbody cage with the macro, micro, and nano level features of 3D titanium with the imaging characteristics and device stiffness of PEEK, the best of both in one device.”